At least 39 people – including 12 children – have been killed in a blast that brought down a building in Syria’s mainly rebel-held north-western province of Idlib, reports say.
The building in the Sarmada town is said to have contained munitions belonging to an arms trafficker.
Dozens of people are still missing, a monitor and correspondents say.
Idlib is the last major rebel-held area, and is expected to be the next target for Syrian armed forces.
In recent months, the Syrian government, backed by Russia and Iran, has made major advances in its offensive against a number of rebel and jihadist groups across Syria.
On Sunday, rescuers in Sarmada used bulldozers to remove the rubble and pull out trapped people, an AFP correspondent in the town near the Turkish border reported.
Hatem Abu Marwan, a member of the Idlib civil defence team, said that “buildings full of civilians were reduced to rubble,” the news agency said.
Meanwhile, the UK-based Syrian Observatory for Human Rights (SOHR) said that there were still dozens of people missing.
Some reports suggest the number killed could be higher.
Most of those in the building are believed to have belonged to the families of jihadist fighters who have taken refuge in Idlib after being driven out of other areas of Syria.
The cause of the explosion was not immediately known.
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Deadly fire breaks out at Taiwan hospital

At least nine people have been killed in a fire at a hospital in Taiwan, state media has reported.
The fire broke out in a ward on the seventh floor of the hospital in New Taipei City early on Monday.
About 16 other people, including patients and staff, remain in a critical condition.
The cause of the fire is not yet clear, though media reports say it could have been started by an electrical fault in a moveable bed.
Reports say 33 patients and three staff members were evacuated from the Weifu hospital in the northern region of the city after a fire broke out at 04:36 on Monday (20:36 GMT Sunday).
According to state media outlet CNA, police found that the ward was not equipped with “required smoke exhaust equipment.”
The BBC reports that fires are common in Taiwan where fire prevention measures are not strictly enforced.
In 2012, a hospital fire left 12 patients killed and at least 60 more injured.
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Spain festival collapse in Vigo injures dozens
Dozens of people have been injured, four seriously, after a section of wooden promenade collapsed at an urban sports and music festival in Spain.
The seafront platform had been packed with people watching a rap artist at the two-day O Marisquino event in the north-west city of Vigo, in Galicia.
More than 130 people are being treated for injuries or shock, local media say.
Some people on the platform, which measured 30m (98ft) long and 10m wide, fell into the sea, reports say.
Witnesses reported scenes of panic as people tried to scramble to safety.
Several emergency teams attended to the injured, and divers were sent into the sea to check that no-one was trapped beneath the structure.
Police confirmed that there were no known fatalities.
According to reports the incident happened shortly before midnight as a crowd was listening to the Mallorcan rap artist Rels B.
In a tweet, he wished “strength” to the injured and advised anyone worried about friends or relatives to contact an emergency information point set up by festival organisers.
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Unite the Right: White nationalists outnumbered at Washington rally

White nationalists have staged a rally near the White House in Washington, but were far outnumbered by counter-protesters.
About 20 far-right supporters attended the demonstration, which came a year after violence in Charlottesville, Virginia, that left one person dead.
Hundreds of chanting opponents staged their own rally nearby, denouncing white supremacy and racism.
The two sides were kept apart by a heavy police presence.
About 400 people had initially been expected at the “Unite the Right 2” rally but on the day nowhere near that number took part.
The white nationalists were escorted by police officers to Lafayette Square, in front of the White House, and were heckled along the route by a larger group of counter-protesters chanting “shame” and “get out of my city.”
Tight security was in place and authorities banned all firearms from the area.
After about two hours, under heavy rain, the rally ended and supporters were escorted out of the area in two police vans.
A larger group of counter-protesters meanwhile gathered at Freedom Plaza, at one end of Pennsylvania Avenue that leads to the US Capitol, chanting and waving banners.
Last year’s far-right rally in Charlottesville was one of the largest gatherings of white nationalists in America in decades.
The march had been organised to protest against plans to remove a statue of a general who had fought for the pro-slavery Confederacy during the US Civil War.
Heather Heyer, 32, was killed after a neo-Nazi driver ploughed his car into a group of anti-racist protesters.
Dozens of other people were injured in violence between the two groups.
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Turkey pledges action to calm markets
Turkey has pledged it will take action to calm markets after the lira plunged to a new record low in Asian trading.
The details would be unveiled shortly, the country’s finance minister told Turkish newspaper Hurriyet.
“From Monday morning onwards our institutions will take the necessary steps and will share the announcements with the market,” Berat Albayrak said.
On Friday, the lira lost 20% of its value versus the dollar. It had already fallen more than 40% in the past year.
Mr. Albayrak said the country would “act in a speedy manner” and its plan included help for the banks and small and medium-sized businesses most affected by the dramatic volatility in the lira.
His assurance came after Turkey’s president blamed the lira’s plunge on a plot against the country.
“What is the reason for all this storm in a tea cup? There is no economic reason… This is called carrying out an operation against Turkey,” he said.
Recep Erdogan once again urged Turks to sell dollars and buy liras to help boost the currency.
“I am specifically addressing our manufacturers: Do not rush to the banks to buy dollars… You should know that to keep this nation standing is also the manufacturers’ duty,” he said.
Experts have blamed the drop in the lira on fears the country is falling into an economic crisis.
The Turkish stock market has also fallen 17%, while government borrowing costs have risen to 18% a year, according to Andrew Walker, the BBC World Service economics correspondent.
Meanwhile, inflation has hit 15%.
Investors are worried that Turkish companies that borrowed heavily to profit from a construction boom may struggle to repay loans in dollars and euros, as the weakened lira means there is now more to pay back.
Then there are Turkey’s worsening relations with the US. Donald Trump’s administration hit Turkey’s justice and interior ministers with sanctions last week, a reaction to the detention of American pastor, Andrew Brunson, who has been held for nearly two years over alleged links to Turkish political groups.
The US dealt Turkey and the lira a further blow in a tweet on Friday, in which Mr. Trump said he had approved the doubling of tariffs on Turkish steel and aluminium.
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Killer whale mother finally lets dead newborn calf go, after 17 days.
A killer whale has stopped carrying her dead newborn calf after at least 17 days, during which she covered 1,000 miles (1,600km), scientists say.
The whale “vigorously chased a school of salmon with her pod-mates in Haro Strait” off Canada’s Vancouver Island, the Center for Whale Research said.
“Her tour of grief is now over and her behaviour is remarkably frisky.”
Killer whales have been known to carry dead calves for a week, but scientists believe this mother “sets a record.”
The mother whale – known as J35 – has captivated the world’s attention in the past few days.
“Telephoto digital images taken from shore show that this mother whale appears to be in good physical condition,” CWR said in a statement on Saturday.
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“The carcass has probably sunk to the bottom of these inland marine waters of the Salish Sea [between Canada and the US], and researchers may not get a chance to examine it for necropsy (autopsy of an animal).”
The mother whale was first spotted carrying her dead calf on 24 July, off the shore of Vancouver Island.
The calf is believed to have died the same day.
The cause of death is unknown.
Both Canada and the US list the Southern Resident killer whale as endangered.
The whales depend on Chinook salmon – which have been in dramatic decline in recent years – for food.